Complement-mediated neutralization of canine distemper virus in vitro: cross-reaction between vaccine Onderstepoort and field KDK-1 strains with different hemagglutinin gene characteristics.
نویسندگان
چکیده
The properties of neutralization of antigens of canine distemper virus Onderstepoort and a recent field isolate, KDK-1, were investigated with strain-specific dog sera. A conventional neutralization assay indicated antigenic dissimilarity between the strains; however, when guinea pig complement was included in the reaction mixture, the strains were neutralized with not only the homologous but also the heterologous antibodies.
منابع مشابه
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عنوان ژورنال:
- Clinical and diagnostic laboratory immunology
دوره 9 4 شماره
صفحات -
تاریخ انتشار 2002